Cushings syndrome is associated with excess of which hormone?

• A. Insulin
• B. Estrogen
• C. Thyroxine
• D. Cortisone

Answer: (D)

Cushing's syndrome is a state of too much glucocorticoids, with cortisol being the most typical culprit. These hormones come from the adrenal cortex and drive features like increased glucose production, protein breakdown, fat redistribution, and anti-inflammatory effects that lead to the characteristic appearance and metabolic changes. Cortisone is closely related to cortisol and part of the same hormone family; the body also converts between these forms, so a state of excess glucocorticoids manifests as the Cushingoid picture. The other options—insulin, estrogen, and thyroxine—are associated with different conditions and bodily systems, not Cushing's syndrome.