Excess cortisone leading to moon face, hump back, fat neck, diabetes, and hirsutism are symptoms of which syndrome?

• A. Addison's disease
• B. Graves' disease
• C. Cushings syndrome
• D. Hashimoto's thyroiditis

Answer: (C)

Excess cortisol causes Cushing's syndrome. The facial rounding (moon face) and a fatty hump on the upper back reflect fat redistribution from high cortisol levels, while central obesity and a fatty neck are common. Cortisol also raises glucose production and causes insulin resistance, leading to diabetes, and increased androgen effects can produce hirsutism. This combination is not typical of Addison's disease (cortisol deficiency), Graves' disease (hyperthyroidism), or Hashimoto's thyroiditis (hypothyroidism), making Cushing's syndrome the best fit.